Capturing changes in gene expression dynamics by gene set differential coordination analysis
نویسندگان
چکیده
منابع مشابه
Quantitative set analysis for gene expression: a method to quantify gene set differential expression including gene-gene correlations
Enrichment analysis of gene sets is a popular approach that provides a functional interpretation of genome-wide expression data. Existing tests are affected by inter-gene correlations, resulting in a high Type I error. The most widely used test, Gene Set Enrichment Analysis, relies on computationally intensive permutations of sample labels to generate a null distribution that preserves gene-gen...
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ژورنال
عنوان ژورنال: Genomics
سال: 2011
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2011.09.001